Kidney Cancer

Each year, nearly 75,000 people in the United States are diagnosed with kidney cancer, and approximately 15,000 die from the disease.

Questions and Answers

What are the Warning Signs of Kidney Cancer?

Kidney cancer often doesn’t cause noticeable symptoms in its early stages. As the disease progresses, however, some people may experience symptoms such as:

  • Blood in the urine (hematuria)

  • Persistent pain in the back or side

  • Loss of appetite

  • Unintended weight loss

  • Fatigue

  • Intermittent fever

If you notice any of these symptoms—especially blood in your urine—it’s important to schedule a medical evaluation. Early diagnosis can play a key role in successfully treating kidney cancer and other conditions affecting the kidneys and urinary tract.

What are the Risk Factors for Kidney Cancer?

Although researchers have not identified a single cause of kidney cancer, several factors may increase your risk of developing the disease. Common risk factors include:

  • Aging

  • Smoking

  • Obesity

  • High blood pressure

  • Long-term dialysis

  • A family history of kidney cancer

Your risk may also be higher if you have certain inherited conditions, such as von Hippel–Lindau disease or Birt-Hogg-Dubé syndrome.

How is Kidney Cancer Diagnosed?

Your urologist begins by reviewing your symptoms, medical history, and lifestyle factors. They also perform a physical exam and may order blood tests and a urinalysis to evaluate your overall kidney and urinary tract health.

If kidney cancer is suspected, imaging tests such as CT scans or MRI may be used to look for abnormal growths on the kidneys. When imaging reveals suspicious tissue, a biopsy may be performed to determine whether the growth is cancerous and to help identify the stage of the disease.

In some cases, your doctor may also recommend additional diagnostic tests to better understand the size and location of the tumor. Imaging studies help determine whether the cancer is confined to the kidney or if it has spread to nearby tissues or other organs. This information is important for developing an effective treatment plan tailored to your specific condition.

Your physician may also evaluate your kidney function through specialized blood tests to ensure that your kidneys are working properly. These tests can help guide decisions about treatment options, especially if surgery becomes necessary.

Accurate diagnosis and staging allow your medical team to recommend the most appropriate treatment approach. Early detection of kidney cancer often leads to better outcomes, which is why it’s important to seek medical evaluation if you experience symptoms such as blood in your urine, persistent back or side pain, or unexplained weight loss. Regular follow-up care and monitoring also play an important role in managing kidney health and preventing complications.

How is Kidney Cancer Treated?

If you’re diagnosed with kidney cancer, your doctor will review your treatment options based on the stage and severity of the disease. In many cases, surgery is recommended to remove the tumor or the affected kidney. Most people can live healthy lives with just one kidney, which is able to continue filtering waste from the blood.

Depending on the type and stage of cancer, other treatments may also be considered. These can include cryoablation or radiofrequency ablation to destroy cancer cells, as well as therapies such as immunotherapy, chemotherapy, radiation therapy, or targeted medications that block signals that promote cancer growth.

After treatment, regular follow-up visits and testing are important to monitor your recovery and check for any signs that the cancer has returned. If you have concerns about kidney cancer or notice symptoms such as blood in your urine, schedule an appointment for evaluation and care.